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Prof. Silvana Galderisi is asked, "What is relevant to recovery?"
Filmed at EPA, Vienna, March 2015
Treatment goals are more ambitious than ever and have moved beyond reducing patients’ symptoms, towards their recovery and the chance to lead a fruitful life. But how do we get there? Prof. Galderisi discusses ways to categorise and prioritise factors that interfere with recovery, and in particular, methods to deconstruct broadly defined negative symptoms. She discusses recent research which categorises negative symptoms into subcategories of avolition and poor emotional expression (PEE), and compares their impact on functioning. A better understanding of the pathophysiology of avolition could lead to treatments targeting avoltion, which would have a significant impact on patients’ lives.
Schizophrenia: What is relevant for recovery
The significance of the heterogeneity of negative symptoms
Which are the methods to assess the heterogeneity of negative symptoms?
What is the relationship between avolition, PEE, and functional outcomes?
Deconstruction of broadly defined negative symptoms might be crucial to identify key targets for new treatments to improve patients’ outcome. Which targets are your focus?
Closing remarks and take home message